Scaffold nucleoporins Nup188 and Nup192 share structural and functional properties with nuclear transport receptors

Nucleocytoplasmic transport is mediated roneverhart.com by nuclear pore complexes (NPCs) embedded in the nuclear envelope.About 30 different proteins (nucleoporins, nups) arrange around a central eightfold rotational axis to build the modular NPC.Nup188 and Nup192 are related and evolutionary conserved, large nucleoporins that are part of the NPC s

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